Medical experts at the University Hospital in Erlangen, eastern Germany, have revealed that they have significantly reduced the symptoms of a serious and incurable autoimmune disorder using a therapy technique that was originally developed to treat cancer.
Despite the fact that the treatment has only been tested on five people thus far, independent medical professionals approved of it. Due to the overwhelming statistical evidence, immunologist Falk Hebeh of the Charité Hospital Berlin predicted that this approach would be repeated in further studies.
The medical group led by immunologist Georg Schitt discussed how to treat lupus erythematosus patients with severe symptoms utilising so-called chimeric receptors for T cells in a paper that was published in the scholarly journal Nature Medicine.
Shet claimed that in a high number of these patients, the disease’s symptoms vanished, and the organisation neglected to keep an eye out for any potentially fatal side effects, which are unavoidable when employing this strategy to cure cancer.
It is still unknown if the success experienced by the five patients can be maintained or if it can be applied to other patients, but an outside expert described what happened as a great success, saying that it was “surprising to see such overwhelming success, and this will advance the field of research,” according to rheumatologist Martin Arringer of the University Hospital in Dresden, Germany. He believes that this method can help in the fight against some other autoimmunities.
It is interesting that chimeric receptor T-cell therapy has only recently been applied to the treatment of cancer, despite having demonstrated success in the management of specific leukaemia and lymphoma subtypes. These cells have a particular receptor, known as the chimeric antigen receptor, on their surface. Patients receive chimeric receptors for T cells by blood transfusion, and the T cells use the receptor to go within the body and destroy cancer cells.
However, this approach has a significant drawback in that it is possible for neurological issues to develop during therapy, which could result in extremely severe inflammatory reactions known as cytokine storms because of the immune system’s overreaction.
And now Chet’s team is disclosing that this technique has been used for the first time to treat patients who are not being treated for cancer. a condition that is yet incurable.
German medical professionals create a technique that raises the possibility of an autoimmune disease cure.
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