The publicity department of the Russian Vyatka University reported that the university’s researchers had devised a procedure for creating unique chemicals that quicken tissue mending.
The office claims that thanks to this technology, medications and medical preparations can be made in Russia for use in artificial organ transplantation and injury therapy.
A protein called platelet growth factor encourages the development of fibroblasts and other types of cells that the body uses as building blocks when repairing damaged tissue. The human body only produces a tiny quantity of this chemical.
According to scientists, drugs based on platelet growth factor are frequently utilised in the treatment of injuries and regenerative medicine. due of its strong therapeutic effects. Additionally, it is utilised in the transplantation of synthetic organs and tissues made from stem cells.
Researchers at Vyatka University created a method for producing platelet growth factor synthetically.
According to biotechnology expert Anna-Anastasia Mystrova, there is a counterpart to this technique in existence. However, it has grown more challenging to import these compounds from other countries for a number of reasons. They are also expensive, and supply could run out at any time. New technologies are two to three times more productive than those from other countries.
Scientists converted the yeast Pichia pastoris into a source of this useful chemical by cloning a human gene that encodes the platelet. The researchers claim that they were successful in obtaining a highly stable, pure, and pure PDGF-BB growth factor. A gel-like solution with 100 micrograms of growth factor per millilitre was prototyped by the researchers.
The genetically modified yeast produces a growth factor that is purified by chromatography when methyl alcohol, which this unicellular fungus utilises for energy and carbon, is added.
There is no equivalent technique for extracting a yeast growth factor from the scientific literature. Mystrova asserts that as a result, it is highly likely to be of interest to businesses and nations that need to catch up in this area of biotechnology.
The source is RIA Novosti.
A human gene is inserted into yeast by Russian scientists for therapeutic purposes.
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